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LIVROS
DE CONHECIMENTOS BÁSICOS: Curi, R (2000). Glutamina -
Metabolismo
e Aplicações Clínicas e no Esporte. Sprint, Rio de
Janeiro, RJ, Brasil. Curi, R.; Pompéia, C.; Miyasaka, C.K.;
Procopio,
J. (2002). Entendendo a Gordura - Os Ácidos Graxos. Manole,
São
Paulo,
SP, Brasil. Newsholme, E. A. & Leech, A.R. (1983) Biochemistry for
the Medical Sciences. John Wiley & Sons, London. Newsholme, E.A.
&.
Start, C. (1974) Regulation in Metabolism. John Wiley & Sons,
London.
Lehninger, A. (1982) Bioquímica. Vols. 1, 2, 3 e 4. Edgar
Blucher
Ltda, São Paulo. REFERÊNCIAS BIBLIOGRÁFICAS:
Newsholme,
E.A.; Newsholme, P.; Curi, R. ; Ardawi, M.S.M. A role for muscle in the
immune system and its importance in surgery, trauma, sepsis and burns.
Nutrition, 4:261-268, 1988. Curi, R.; Newsholme, P.; Newsholme, E.A.
Metabolism
of pyruvate by isolated rat mesenteric lymphocytes, lymphocyte
mitochondria
and isolated mouse macrophage. Biochem. J., 250:383-388, 1988. Curi, R.
Metabolic and hormonal adaptations to diet restriction. Nutrition,
8:56-57,
1992. Serrano, M.A.R.; Curi, R.; Parry-Billings, M.; Williams, J.F.;
Newsholme,
E.A. Effects of glucocorticoids on lymphocyte metabolism. Am. J.
Physiol.,
264: E24-E28, 1993. Homem de Bittencourt Júnior, P.I.; Peres,
C.M.;
Yano, M.M.; Hirata, M.; Curi, R. Pyruvate is a lipid precursor for rat
lymphocytes in culture. Evidence for a lipid exporting capacity.
Biochem.
Mol. Biol. Int., 30:631-641, 1993. Lancha Júnior, A.H.; Recco,
M.B.;
Curi, R. Pyruvate carboxylase activity in the heart and skeletal
muscles
of the rat. Evidence for a stimulating effect of exercise. Biochem.
Mol.
Biol. Int., 32: 483-489, 1994. Costa Rosa, L.F.B.P.; Safi, D.A.; Curi,
R. Effect of thioglycollate and BCG stimuli on glucose and glutamine
metabolism
in rat macrophage. J. Leukoc. Biol., 56:10-14,1994. Homem de
Bittencourt,
Jr., P.I.; Yano, M.M.; Hirata, M.H.; Williams, J.F.; Curi, R. Evidence
that prostaglandins modulate lipogenesis in cultured lymphocytes - A
comparison
with its effect on macrophages and tumor cells. Biochem. Mol. Biol.
Int.,
33: 463-475, 1994.Fernandes, L.C.; Curi, R. Reversion of Walker 256
tumor
cachexia by insulin treatment. Possible mechanism involved and
perspectives
for future research. Endocrine-Related Cancer, 4: 1-10, 1997. Pithon
Curi,
T.C.; Pires de Melo, M.; De Azevedo, R.; Zorn, T.M.T.; Curi, R.
Glutamine
utilization by rat neutrophils. Presence of phosphate-dependent
glutaminase.
Am. J. Physiol. 273: C1124-C1129, 1997. Peres, C.M.; Homem de
Bittencourt,
Jr., P.I.; Costa, M.; Curi, R.; Williams, J.F. Evidence for the
transference
in culture of [14C]-labelled fatty acids from macrophages to
lymphocytes.
Biochem. Mol. Biol. Int. 43: 1137-1144, 1997. Homem de Bittencourt,
Jr.,
P.I.; Curi, R. Transfer of cholesterol from macrophages to lymphocytes
in culture. Biochem. Mol. Biol. Int. 44: 347-362, 1998. Otton, R.;
Graziola,
F.; Hirata, M.H.; Curi, R.; John F. Williams. Dietary fats alter the
activity
and expression of glucose-6-phosphate dehydrogenase in rat lymphoid
cells
and tissues. Biochem. Mol. Biol. Int., 46: 529-536, 1998. Bacis Ceddia,
R.; William, Jr., W.N.; Bessa-Lima, F.; Curi, R. Leptin inhibits
insulin
stimulated incorporation of glucose into lipids and stimulates glucose
decarboxylation in isolated rat adipocytes. J. Endocrinol., 158: R7-R9,
1998. Bacis Ceddia, R.; William, Jr., W.N.; Curi, R. Comparing effects
of leptin and insulin on glucose metabolism in skeletal muscle:
evidence
for na effect of leptin on glucose uptake and decarboxylation. Int. J.
Obes. Relat. Metab. Disord., 22: 01-08,1998. Curi, R.; Newsholme, P.;
Pithon-Curi,
T.C.; Pires-de-Melo, M.; Garcia, C.; Homem-de-Bittencourt, Jr., P.I.;
Guimarães,
A R.P. Metabolic fate of glutamine in lymphocytes, macrophages and
neutrophils.
Braz. J. Med. Biol. Res., 32: 15-21, 1999. Newsholme, P.; Curi, R.;
Pithon-Curi,
T.C.; Murphy, C.J.; Garcia, C.; Pires-de-Melo, M. Glutamine metabolism
by lymphocytes, macrophages and neutrophils. Its importance in health
and
disease. J. Nutr. Biochem., 10: 316-324, 1999. Garcia, C., Pithon-Curi,
T.C.; Firmano, M.L.; De-Mello, M. P.; Newsholme, P.; Curi, R. Effect of
adrenaline on glucose and glutamine metabolism and superoxide
production
by rat neutrophils. Clinical Sci., 96: 549-555, 1999. Bacis-Ceddia, R.;
Lopes, G.; Souza, H.M.; Borba-Murad, G.R.; William, Jr., W.N.; Bazotte,
R.B.; Curi, R. Acute effects of leptin on glucose metabolism of in situ
rat perfused livers and isolated hepatocytes. Int. J. Obes. Relat.
Metab.
Disord., 23: 1207-1212, 1999. Peres, C.M.; Procópio, J.; Costa,
M.; Curi, R. Thioglycollate stimulation modulates the incorporation and
oxidation of fatty acids by rat macrophages. Lipids, 34: 1193-7, 1999.
Nishiyama-Naruke, A; Curi, R. Phosphatidylcholine participates in the
interaction
between macrophages and lymphocytes.. Am. J. Physiol. 278:C554-60,
2000.
Pompéia, C.; Lopes, L.R.; Miyasaka, C.K.; Procópio, J.;
Sannomiya,
P. and Curi, R. Effect of fatty acids on leukocyte function. Braz. J.
Med.
Biol. Res., 33: 1255-1268, 2000. Nishiyama, A.; Cavaglieri, C.R; Curi,
R.; Calder, C.P. Arachidonic acid-containing phosphatidylcholine
inhibits
lymphocyte proliferation and decreases interleukin-2 and interferon-g
production
from concanavalin A-stimulated rat lymphocytes. Biochem. Biophis. Acta,
1487: 50-60, 2000. Bacis-Ceddia, R.; William, Jr., W.N.; Lima, F.B.;
Flandin,
P.; Curi, R.; Giacobino, J.P. Leptin stimulates uncoupling protein-2
mRNA
expression and krebs cycle activity and inhibits lipid synthesis in
isolated
rat white adipocytes. Eur. J. Biochem., 267:5952-5958. 2000.
Bacis-Ceddia,
R.; William Jr., N.W.; Curi, R. The response of skeletal muscle to
leptin.
Front. Biosc., 6: 90-97, 2001. Freitas, J.J.S.; Pompéia, C.;
Miyasaka,
C.K.; Curi, R. Walker-256 tumor growth causes oxidative stress in rat
brain.
J. Neurochem., 77: 655-663, 2001. Sampaio, S.C.; Sousa-e-Silva, M.C.C.;
Borelli, P.; Curi, R.; Cury, Y. Crotalus Durissus Terrificus snake
venom
regulates macrophage metabolism and function. J. Leukoc. Biol., 70:
551-558,
2001. Miyasaka, C.K.; Mendonça, J.R.; Nishiyama, A.;
Alves-de-Souza,
J.A.; Pires-de-Melo, M.; Pithon-Curi, T.C.; Curi, R. Comparative
effects
of fish oil given by gavage and fish-oil-enriched diet on leukocytes.
Life
Sci., 69: 1739-1751, 2001. Otton, R.; Mendonça, J.R.; Curi, R.
Diabetes
causes marked changes in lymphocyte metabolism. J. Endocrinol. 174:
55-61.
2002. Pithon-Curi, T. C.; Levada, A. C.; Lopes, L. R.; Doi, S. Q.;
Curi,
R. Glutamine plays a role for superoxide production and the expression
of p47phox, p22phox, and gp91phox in rat neutrophils. Clinical Science.
2002 (in press). Newsholme, E.A.; Newsholme, P.; Curi, R. ; Ardawi,
M.S.M.
A role for muscle in the immune system and its importance in surgery,
trauma,
sepsis and burns. Nutrition, 4:261-268, 1988. Curi, R.; Newsholme, P.;
Newsholme, E.A. Metabolism of pyruvate by isolated rat mesenteric
lymphocytes,
lymphocyte mitochondria and isolated mouse macrophage. Biochem. J.,
250:383-388,
1988. Curi, R. Metabolic and hormonal adaptations to diet restriction.
Nutrition, 8:56-57, 1992. Serrano, M.A.R.; Curi, R.; Parry-Billings,
M.;
Williams, J.F.; Newsholme, E.A. Effects of glucocorticoids on
lymphocyte
metabolism. Am. J. Physiol., 264: E24-E28, 1993. Homem de Bittencourt
Júnior,
P.I.; Peres, C.M.; Yano, M.M.; Hirata, M.; Curi, R. Pyruvate is a lipid
precursor for rat lymphocytes in culture. Evidence for a lipid
exporting
capacity. Biochem. Mol. Biol. Int., 30:631-641, 1993. Lancha
Júnior,
A.H.; Recco, M.B.; Curi, R. Pyruvate carboxylase activity in the heart
and skeletal muscles of the rat. Evidence for a stimulating effect of
exercise.
Biochem. Mol. Biol. Int., 32: 483-489, 1994. Costa Rosa, L.F.B.P.;
Safi,
D.A.; Curi, R. Effect of thioglycollate and BCG stimuli on glucose and
glutamine metabolism in rat macrophage. J. Leukoc. Biol.,
56:10-14,1994.
Homem de Bittencourt, Jr., P.I.; Yano, M.M.; Hirata, M.H.; Williams,
J.F.;
Curi, R. Evidence that prostaglandins modulate lipogenesis in cultured
lymphocytes - A comparison with its effect on macrophages and tumor
cells.
Biochem. Mol. Biol. Int., 33: 463-475, 1994. Fernandes, L.C.; Curi, R.
Reversion of Walker 256 tumor cachexia by insulin treatment. Possible
mechanism
involved and perspectives for future research. Endocrine-Related
Cancer,
4: 1-10, 1997. Pithon Curi, T.C.; Pires de Melo, M.; De Azevedo, R.;
Zorn,
T.M.T.; Curi, R. Glutamine utilization by rat neutrophils. Presence of
phosphate-dependent glutaminase. Am. J. Physiol. 273: C1124-C1129,
1997.
Peres, C.M.; Homem de Bittencourt, Jr., P.I.; Costa, M.; Curi, R.;
Williams,
J.F. Evidence for the transference in culture of [14C]-labelled fatty
acids
from macrophages to lymphocytes. Biochem. Mol. Biol. Int. 43:
1137-1144,
1997. Homem de Bittencourt, Jr., P.I.; Curi, R. Transfer of cholesterol
from macrophages to lymphocytes in culture. Biochem. Mol. Biol. Int.
44:
347-362, 1998. Otton, R.; Graziola, F.; Hirata, M.H.; Curi, R.; John F.
Williams. Dietary fats alter the activity and expression of
glucose-6-phosphate
dehydrogenase in rat lymphoid cells and tissues. Biochem. Mol. Biol.
Int.,
46: 529-536, 1998. Bacis Ceddia, R.; William, Jr., W.N.; Bessa-Lima,
F.;
Curi, R. Leptin inhibits insulin stimulated incorporation of glucose
into
lipids and stimulates glucose decarboxylation in isolated rat
adipocytes.
J. Endocrinol., 158: R7-R9, 1998. Bacis Ceddia, R.; William, Jr., W.N.;
Curi, R. Comparing effects of leptin and insulin on glucose metabolism
in skeletal muscle: evidence for na effect of leptin on glucose uptake
and decarboxylation. Int. J. Obes. Relat. Metab. Disord., 22:
01-08,1998.
Curi, R.; Newsholme, P.; Pithon-Curi, T.C.; Pires-de-Melo, M.; Garcia,
C.; Homem-de-Bittencourt, Jr., P.I.; Guimarães, A R.P. Metabolic
fate of glutamine in lymphocytes, macrophages and neutrophils. Braz. J.
Med. Biol. Res., 32: 15-21, 1999.Newsholme, P.; Curi, R.; Pithon-Curi,
T.C.; Murphy, C.J.; Garcia, C.; Pires-de-Melo, M. Glutamine metabolism
by lymphocytes, macrophages and neutrophils. Its importance in health
and
disease. J. Nutr. Biochem., 10: 316-324, 1999. Garcia, C., Pithon-Curi,
T.C.; Firmano, M.L.; De-Mello, M. P.; Newsholme, P.; Curi, R. Effect of
adrenaline on glucose and glutamine metabolism and superoxide
production
by rat neutrophils. Clinical Sci., 96: 549-555, 1999. Bacis-Ceddia, R.;
Lopes, G.; Souza, H.M.; Borba-Murad, G.R.; William, Jr., W.N.; Bazotte,
R.B.; Curi, R. Acute effects of leptin on glucose metabolism of in situ
rat perfused livers and isolated hepatocytes. Int. J. Obes. Relat.
Metab.
Disord., 23: 1207-1212, 1999. Peres, C.M.; Procópio, J.; Costa,
M.; Curi, R. Thioglycollate stimulation modulates the incorporation and
oxidation of fatty acids by rat macrophages. Lipids, 34: 1193-7, 1999.
Nishiyama-Naruke, A; Curi, R. Phosphatidylcholine participates in the
interaction
between macrophages and lymphocytes.. Am. J. Physiol. 278:C554-60,
2000.
Pompéia, C.; Lopes, L.R.; Miyasaka, C.K.; Procópio, J.;
Sannomiya,
P. and Curi, R. Effect of fatty acids on leukocyte function. Braz. J.
Med.
Biol. Res., 33: 1255-1268, 2000. Nishiyama, A.; Cavaglieri, C.R; Curi,
R.; Calder, C.P. Arachidonic acid-containing phosphatidylcholine
inhibits
lymphocyte proliferation and decreases interleukin-2 and interferon-g
production
from concanavalin A-stimulated rat lymphocytes. Biochem. Biophis. Acta,
1487: 50-60, 2000. Bacis-Ceddia, R.; William, Jr., W.N.; Lima, F.B.;
Flandin,
P.; Curi, R.; Giacobino, J.P. Leptin stimulates uncoupling protein-2
mRNA
expression and krebs cycle activity and inhibits lipid synthesis in
isolated
rat white adipocytes. Eur. J. Biochem., 267:5952-5958. 2000.
Bacis-Ceddia,
R.; William Jr., N.W.; Curi, R. The response of skeletal muscle to
leptin.
Front. Biosc., 6: 90-97, 2001. Freitas, J.J.S.; Pompéia, C.;
Miyasaka,
C.K.; Curi, R. Walker-256 tumor growth causes oxidative stress in rat
brain.
J. Neurochem., 77: 655-663, 2001. Sampaio, S.C.; Sousa-e-Silva, M.C.C.;
Borelli, P.; Curi, R.; Cury, Y. Crotalus Durissus Terrificus snake
venom
regulates macrophage metabolism and function. J. Leukoc. Biol., 70:
551-558,
2001. Miyasaka, C.K.; Mendonça, J.R.; Nishiyama, A.;
Alves-de-Souza,
J.A.; Pires-de-Melo, M.; Pithon-Curi, T.C.; Curi, R. Comparative
effects
of fish oil given by gavage and fish-oil-enriched diet on leukocytes.
Life
Sci., 69: 1739-1751, 2001. Otton, R.; Mendonça, J.R.; Curi, R.
Diabetes
causes marked changes in lymphocyte metabolism. J. Endocrinol. 174:
55-61.
2002. Pithon-Curi, T. C.; Levada, A. C.; Lopes, L. R.; Doi, S. Q.;
Curi,
R. Glutamine plays a role for superoxide production and the expression
of p47phox, p22phox, and gp91phox in rat neutrophils. Clinical Science.
2002 (in press). Pithon-Curi, T. C.; Levada, A. C.; Lopes, L. R.; Doi,
S. Q.; Curi, R. Glutamine plays a role for superoxide production and
the
expression of p47phox, p22phox, and gp91phox in rat neutrophils.
Clinical
Science. 2002 (in press). |
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